Strupenost Za Podgane (holekalciferol) Pri Konjih

2024 Avtor: Daisy Haig | [email protected]. Nazadnje spremenjeno: 2023-12-17 03:13

Zastrupitev s holekalciferolom pri konjih

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Holikalciferol (vitamin D3) je aktivna sestavina mnogih vrst podganjih strupov. Visok odmerek holikaciferola bo povzročil destabilizacijo kalcija v telesu, kar bo povzročilo hiperkalciemijo in sčasoma povzročilo kalcifikacijo tkiv in organov telesa. Povišana raven kalcija v krvi bo povzročila hude poškodbe ledvic.

Konji bodo občasno prišli v stik s konjsko krmo, ki je bila kontaminirana s holikalnim ciferolom, morda takrat, ko je strup odložen v skladiščne prostore in je zaradi tega nenamerno zastrupljen. To se pogosto zgodi brez vednosti oskrbnika. Do zaužitja te spojine lahko pride tudi, če krmo neprimerno mešamo ali pripravljamo, ali če preveč vnemo dajemo dodatek vitamina D3.

Simptomi

• Izguba apetita (anoreksija)
• Izguba teže
• Depresija
• Težave z dihanjem (dispneja)
• Prekomerna žeja (polidipsija) s povečano porabo vode
• Povečana tvorba urina (poliurija)
• Slabost
• Povečan srčni utrip
• Togost okončin
• Ležanje
• Smrt

Vzroki

• Zaužitje holikaciferola, običajno nenamerno
• Običajno vključuje kontaminacijo hrane s podganjim strupom

Diagnoza

Vaš veterinar lahko diagnosticira toksičnost za holikciferol tako, da vzame vzorec krvi v laboratorij, ki bo izmeril koncentracijo spojine v serumu. Bolj rutinsko odkrivanje krvi bo pokazalo povišano raven fosforja in kalcija ter znake okvare ledvic.

Zdravljenje

Zdravljenje zastrupitve s holialciferolom se razlikuje od primera do primera, odvisno od količine zaužitega strupa in resnosti simptomov.

Najpogostejši pristop k zdravljenju je običajno povezan z omejevanjem količine vitamina D, ki se vnaša s hrano in dodatki. Morda boste dobili kalcijev kalcij, saj bo to zmanjšalo absorpcijo kalcija v črevesju. Začeti je treba zdravljenje tudi zaradi odpovedi ledvic. To je običajno podporna oskrba in zahteva dajanje velikih količin IV tekočine.

Življenje in upravljanje

Okrevanje po tej toksikozi je lahko dolgotrajno in pogosto nekoristno, saj poapnenja tkiv in odpovedi ledvic ni mogoče razveljaviti. Napoved je varovana in pogosto je izvoljena evtanazija.

Preprečevanje

Čeprav nenamernega zaužitja ni mogoče preprečiti, se občasno tovrstna toksikoza pojavi zaradi slabega upravljanja z vitaminskimi dodatki. Preden začnete s konjem na kakršen koli dodatek, se o tem pogovorite s svojim veterinarjem.